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NALM-1 is a lymphoblast cell line that was isolated from the peripheral blood of a three-year-old, female patient with leukemia. This cell line was deposited by J Minowada and can be used in immunology and immune system disorder research.
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94T778 is a cell line exhibiting fibroblast-like morphology that was isolated in 1994 from the retroperitoneum of a White 69-year-old female with liposarcoma. It was established from the second recurrence of the tumor from the same individual from which the 93T449 cell line (ATCC CRL-3043) was derived. The MDM2 amplification present in this cell line can be used as a model for testing new drugs and cancer research.
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The PathHunter BAI2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of BAI2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BAI2 and EA-tagged β-Arrestin-2. Activation of BAI2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
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ATCC 51663-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 51663™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
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The PathHunter U2OS EphB2 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB2 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EphB2 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
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Mycoplasma genitalium strain G37 (ATCC 33530™) is a whole-genome sequenced type strain isolated from the urethra of a male patient with non-gonococcal urethritis. This bacterial culture has applications in infectious disease and sexually transmitted disease research. This culture produces a surface attachment protein.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
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Enterococcus faecium is a multidrug-resistant, whole-genome sequenced bacterium that was isolated from human feces. This strain is confirmed by PCR to carry the vanA vancomycin resistance gene. It has applications in antimicrobial resistance research and drug development.
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The ChemiScreen PAR2 Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of F2RL1 surface expression. ChemiScreen membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
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Saccharomyces cerevisiae strain EBY100 (ATCC MYA-4941™) is a genetically engineered yeast used in yeast surface display for protein and antibody screening. Derived from BJ5465, it contains genomic insertion of AGA1 under GAL promoter with a URA3 marker.
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